PurePrep MTS for (u)HMW
Beadless DNA purification for (ultra) High Molecular Weight

Modified Tipcomb Surface (MTS) technology is an innovative alternative to bead-based purification based on a proven, longstanding technique of “spooling”. Utilizing a mild buffer and modified tipcomb surfaces to extract DNA from a range of samples.

PurePrep MTS enables efficient extraction for application where DNA of large fragment sizes are required. Due to the lack of magnetic beads and other shearing, MTS is an ideal solution for any application where (ultra) High Molecular Weight is needed.

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Advantages of PurePrep MTS for (ultra) High Molecular Weight
Due to this gentle method of DNA purification, the high molecular weight MTS buffer system is an ideal solution for applications where DNA of large fragment size is required.

During this process there is no requirement for sample pipetting, no requirement for bead binding and no use of aggressive chemicals, all of which can result in sheared DNA. This method ensures that the final eluted DNA is of very high molecular weight and that short and sheared fragments are in very low abundance.

Features

  • Lower amount of chemical and plastic waste waste reducing carbon footprint
  • Safer operation due to lack of chaotropic salts
  • Gentle extraction method reduces risk of shearing
  • Compatible with automated systems such as the PurePrep 96 and PurePrep Mini

Specifications

With different lysis / binding buffer systems available, we can ensure that this initial crucial step of your purification is as optimized as possible for your project.

If you have an interest in using MTS technology and reagents, please contact us to discuss the possibilities.

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