PurePrep Polymer Capture Cell-free DNA Kit
Bead-based purification kits for circulating cell-free DNA

The PurePrep Polymer Capture Cell-Free DNA kit allows for automated purification of circulating cell-free DNA from plasma or urine samples. The kit combines a unique polymer capture technology for enrichment of biomolecules with a very efficient extraction of DNA using magnetic particles.

The polymer capture step of the process can be implemented with either centrifugation or bead-based capture, depending on the individual customer requirements.

The extraction takes place on the PurePrep Mini, allowing parallel and flexible extraction of 1 to 16 samples.

Purification of circulating cell-free DNA utilizing polymer capture technology
Unlike commonly used methods or kits, the PurePrep Polymer Capture Cell-Free DNA Kit does not start with sample lysis. Instead, the first step involves capturing of free-circulating DNA with a special polymer, after which the polymer is dissolved in a special lysis buffer, followed by automated purification greatly reducing hands-on time.

The patented polymer capture technology in this kit allows for the capture of bio-molecules from larger volumes of starting material. This technology thus makes the purification of circulating cell-free DNA significantly easier and faster.

Features

  • Utilizes a unique polymer capture technology
    • Easy to use protocols (~90 minutes including polymer capture)
    • Greatly reduced hands-on time
  • Optimized for use on PurePrep Mini
  • Compatible with a variety of downstream applications

Specifications

Starting Material:

  • 10 mL urine
  • 5 mL plasma

Isolation Time:

  • ~90 minutes including all steps

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